1428118-12-0
中文名称
阿托伐他汀钙杂质34
英文名称
(3S,5S)-tert-butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
CAS
1428118-12-0
分子式
C37H43FN2O5
分子量
614.75
MOL 文件
1428118-12-0.mol
更新日期
2024/10/11 11:28:10
1428118-12-0 结构式
基本信息
中文别名
阿托伐他汀钙杂质34阿托伐他汀钙杂质(S,S构型)
英文别名
Atorvastatin calcium-25(βS,δS)-Atorvastatin tert-Butyl Ester
Atorvastatin Calcium Hydrate impurity 34
(3S,5S)-tert-butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, 1,1-dimethylethyl ester, (βS,δS)-
1H-?Pyrrole-?1-?heptanoic acid, 2-?(4-?fluorophenyl)?-?β,?δ-?dihydroxy-?5-?(1-?methylethyl)?-?3-?phenyl-?4-?[(phenylamino)?carbonyl]?-?, 1,?1-?dimethylethyl ester, (βS,?δS)?-
Atorvastatin impurity 24/(3S,5S)-Atorvastatin tert-Butyl Ester/(3S,5S)-tert-butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
所属类别
分析化学：药典标准品和杂质标准品应用领域
用途一
(βS,δS)-Atorvastatin tert-Butyl Ester is an intermediate used in the synthesis of (3S,5S)-Atorvastatin Sodium Salt (A791735), which is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.