142846-71-7
142846-71-7 结构式
基本信息
GWTLNSAGYLLGPPPGFSPFR-NH2
Galanin receptorligand M35
GALANIN (1-13)-BRADYKININ (2-9) AMIDE
Galanin (1-13)-Bradykinin (2-9), amide, M35
GALANIN FRAGMENT (1-13)-BRADYKININ*FRAGMENT (2-9)AM
GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2
H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2
L-Argininamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/08/19 | HY-P1840 | GALANIN (1-13) - BRADYKININ (2-9) AMIDE Galanin Receptor Ligand M35 | 142846-71-7 | 1mg | 2000元 |
| 2024/08/19 | HY-P1840 | GALANIN (1-13) - BRADYKININ (2-9) AMIDE Galanin Receptor Ligand M35 | 142846-71-7 | 5mg | 4200元 |
| 2024/08/19 | HY-P1840 | GALANIN (1-13) - BRADYKININ (2-9) AMIDE Galanin Receptor Ligand M35 | 142846-71-7 | 10mg | 6510元 |
常见问题列表
Kd: 0.1 nM (galanin receptor)
Ki: 0.11 nM (human galanin receptor type 1), 2.0 nM (human galanin receptor type 2)
Galanin Receptor Ligand M35 has a dual effect on the galanin mediated inhibition of Forskolin stimulated cyclic AMP production in Rin m 5F cells. Co-applied with galanin (10 nM), Galanin Receptor Ligand M35 at low concentrations (1 nM) is able to reverse the inhibitory effect of galanin. But when present at higher concentrations (15 and 30 nM), Galanin Receptor Ligand M35 acts as a galanin receptor agonist, inhibiting the forskolin stimulated production of cAMP.
Galanin Receptor Ligand M35 (6 nM/10 μL; i.c.v.) improves the ability of the male Sprague-Dnwley rats to acquire the swim maze task.