1431697-80-1
中文名称
(3R,4S)-REL-N,4-二甲基-1-苄基-3-哌啶胺
英文名称
(3R,4S)-1-benzyl-N,4-diMethylpiperidin-3-aMine
CAS
1431697-80-1
分子式
C14H22N2
分子量
218.34
MOL 文件
1431697-80-1.mol
1431697-80-1 结构式
基本信息
中文别名
托法替布杂质23托法替尼-IMZ41
托法替尼杂质M4-RS
(3R,4S)-REL-N,4-二甲基-1-苄基-3-哌啶胺
3R,4S-1-苄基-4-甲基-3-甲氨基-哌啶盐酸盐(托法替尼杂质)
3R,4S-1-苄基-4-甲基-3-甲氨基-哌啶盐酸盐(托法替尼杂质) 100MG
英文别名
trans-1-benzyl-N,4-diMethylpiperidin-3-aMine(3R,4S)-1-benzyl-N,4-diMethylpiperidin-3-aMine
(3R,4S)-rel-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine
rel-(3R,4S)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine
3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3R,4S)-rel-
应用领域
用途一
(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an intermediate in the synthesis of (3R,4S)-Tofacitinib (T528000). (3R,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.