144208-62-8
中文名称
2-(2-(((苄氧基)羰基)氨基)乙氧基)乙基 4-甲基苯磺酸酯
英文名称
Toluene-4-sulfonic acid 2-(2-benzyloxycarbonylamino-ethoxy)-ethyl ester
CAS
144208-62-8
分子式
C19H23NO6S
分子量
393.45
MOL 文件
144208-62-8.mol
更新日期
2024/06/24 17:54:14
144208-62-8 结构式
基本信息
中文别名
2-(2-(((苄氧基)羰基)氨基)乙氧基)乙基 4-甲基苯磺酸酯 英文别名
2-(2-(((benzyloxy)carbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonateToluene-4-sulfonic acid 2-(2-benzyloxycarbonylamino-ethoxy)-ethyl ester
应用领域
用途一
2-(2-(((Benzyloxy)carbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate is a PEG linker containing a tosyl group and benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.