1446194-56-4
中文名称
硼替佐米杂质H
英文名称
bortezoMib iMpurity H
CAS
1446194-56-4
分子式
C19H24N4O2
分子量
340.42
MOL 文件
1446194-56-4.mol
更新日期
2024/07/31 18:35:05
1446194-56-4 结构式
基本信息
中文别名
硼替佐米杂质S硼替佐米杂质H
硼替佐米杂质05
硼替佐米杂质 11
BORTEZOMIBQ杂质 H
N-[(1S)-2-[(3-甲基丁基)氨基]-2-氧代-1-(苯基甲基)乙基]-2-吡嗪甲酰胺
英文别名
Bortezomib Imp.HBortezomib Impurity S
bortezoMib iMpurity H
(S)-N-(1-(isopentylaMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
2-Pyrazinecarboxamide, N-[(1S)-2-[(3-methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-
Bortezomib impurity 11/(S)-N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
所属类别
分析化学：药典标准品和杂质标准品
应用领域
用途一
N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is an impurity of Bortezomib (B675700) which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.