1508-76-5
中文名称
丙环定盐酸盐
英文名称
PROCYCLIDINE HYDROCHLORIDE
CAS
1508-76-5
分子式
C19H30ClNO
分子量
323.9
MOL 文件
1508-76-5.mol
更新日期
2023/09/08 15:48:11
1508-76-5 结构式
基本信息
中文别名
开马君卡马特灵
丙环定盐酸盐
盐酸丙环定 USP标准品
1-苯基-1-环己基-3-吡咯烷丙醇盐酸盐
英文别名
D00782kemadrin
Osnervan
Arpicolin
Kemadrin (tn)
PROCYCLIDINE HCL
kemadrinhydrochloride
PROCYCLIDINE HYDROCHLORIDE
(±)-Procyclidine hydrochlorid
Procyclidine hydrochloride (usp)
所属类别
分析化学：药典标准品和杂质标准品安全数据
警示词警告
危险性描述H315-H319
危险品标志Xn
危险类别码20/21/22
安全说明36
WGK Germany3
RTECS号UY1926000
海关编码2933997500
毒性mouse,LD50,intravenous,14mg/kg (14mg/kg),BEHAVIORAL: TREMORLUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 383, 1955.
应用领域
用途1
An anticholinergic drug used in the treatment parkinson鈥檚 disease. It is also used to treat patients suffering from drug-induced parkinsonism, akathisia and acute dystonia.丙环定盐酸盐价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/11/08 | HY-B1487 | 丙环定盐酸盐 Procyclidine hydrochloride | 1508-76-5 | 100mg | 600元 |
| 2024/11/08 | HY-B1487 | 丙环定盐酸盐 Procyclidine hydrochloride | 1508-76-5 | 10mM * 1mLin DMSO | 660元 |
常见问题列表
生物活性
Procyclidine hydrochloride 是一种有效的抗胆碱能试剂，也具有NMDA拮抗剂的特性。靶点
NMDA Receptor
体内研究
Procyclidine widely used as anti-parkinsonian agents because of their anti-cholinergic action, is also known to have NMDA antagonist properties. Unlike other NMDA antagonists, these agents-because of their anti-cholinergic action-are devoid of neurotoxic side effects. Procyclidine alleviates thermal hyperalgesia in a dose dependent manner; when a marginally effective dose of the agent is combined with an ineffective dose of an alpha(2) adrenergic agonist (Clonidine or Guanabenz), the combination therapy provides effective and long-lasting relief from neuropathic pain.