152646-95-2
中文名称
2-脱氧-3-O-(9-苯基壬酰基)-2-[3(S)-(9-苯基壬酰氧基)十四烷酰胺基]-4-O-磺基-D-吡喃葡萄糖单钠盐
英文名称
2-Deoxy-3-O-(9-phenylnonanoyl)-2-[3(S)-(9-phenylnonanoyloxy)tetradecanamido]-4-O-sulfo-D-glucopyranose monosodium salt
CAS
152646-95-2
分子式
C50H78NNaO12S
分子量
940.21
MOL 文件
152646-95-2.mol
152646-95-2 结构式
基本信息
中文别名
化合物 T33802ONO-4007 单钠盐
2-脱氧-3-O-(9-苯基壬酰基)-2-[3(S)-(9-苯基壬酰氧基)十四烷酰胺基]-4-O-磺基-D-吡喃葡萄糖单钠盐
英文别名
Ono-4007 sodium salt2-Deoxy-3-O-(9-phenylnonanoyl)-2-[3(S)-(9-phenylnonanoyloxy)tetradecanamido]-4-O-sulfo-D-glucopyranose monosodium salt
[(2R,3R,4R,5R)-1,2-dihydroxy-6-oxo-4-(9-phenylnonanoyloxy)-5-[[(3S)-3-(9-phenylnonanoyloxy)tetradecanoyl]amino]hexan-3-yl] sulfate
应用领域
用途一
Ono 4007 is new synthetic low-toxicity lipid A analog which stimulates the production of tumor necrosis factor-alpha in tumor tissues, resulting in the rejection of transplanted rat hepatoma cells. Studies suggest that ONO-4007 is therapeutically useful for the treatment of TNF-alpha-sensitive tumors and tumor eradication.