1581270-11-2
中文名称
1581270-11-2
英文名称
RIP2 kinase inhibitor 2
CAS
1581270-11-2
分子式
C21H28N4O4S
分子量
432.54
MOL 文件
1581270-11-2.mol
1581270-11-2 结构式
基本信息
中文别名
RIP2抑制剂(RIP2 KINASE INHIBITOR 2) 英文别名
RIPK2-IN-2RIP2 kise inhibitor 2
RIP2 kinase inhibitor 2
4-Quinolinamine, 6-[(1,1-dimethylethyl)sulfonyl]-N-(4,5-dimethyl-1H-pyrazol-3-yl)-7-(2-methoxyethoxy)-
物理化学性质
沸点670.0±55.0 °C(Predicted)
密度1.266±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度DMSO : 5 mg/mL (11.56 mM)
酸度系数(pKa)14.93±0.50(Predicted)
形态Solid
颜色Light yellow to yellow
1581270-11-2价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/08/19 | HY-19761 | 1581270-11-2 RIP2 kinase inhibitor 2 | 1581270-11-2 | 5mg | 2000元 |
| 2024/08/19 | HY-19761 | 1581270-11-2 RIP2 kinase inhibitor 2 | 1581270-11-2 | 10mM * 1mLin DMSO | 2200元 |
| 2024/08/19 | HY-19761 | 1581270-11-2 RIP2 kinase inhibitor 2 | 1581270-11-2 | 10mg | 3200元 |
常见问题列表
生物活性
RIP2 kinase inhibitor 2 是一种受体相互作用蛋白-2 (RIP2) 激酶抑制剂，详细信息请参考专利 WO/2014043437 A1 中的化合物 example 9。靶点
RIP2 Kinase
体外研究
RIP2 kinase inhibitor 2 is a novel prodrug of a quinazolyl amine that inhibits RIP2 kinase. Receptor interacting protein-2 (RIP2) kinase is a TKL family serine/threonine protein kinase involved in innate immune signaling. Following activation, RIP2 kinase associates with NODI or NOD2 and appears to function principally as a molecular scaffold to bring together other kinases (TAK1, ΙΚΚα/β/γ) involved in NF-κΒ and mitogen-activated protein kinase activation.