160492-56-8
160492-56-8 结构式
基本信息
中文别名
奥沙奈坦 英文别名
SR142801SR-142801
Osanetant
Osanetant >=98% (HPLC)
N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide
(R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine
N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide
AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
物理化学性质
沸点727.9±60.0 °C(Predicted)
密度1.25
储存条件-20°C
溶解度DMSO：可溶15mg/mL，澄清
酸度系数(pKa)8.33±0.10(Predicted)
形态粉末
颜色白色至米色
旋光性 (optical activity)[α]/D +18 to +24°, c = 1 in methanol
奥沙奈坦价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-14551 | 奥沙奈坦 Osanetant | 160492-56-8 | 1mg | 2320元 |
| 2024/01/25 | HY-14551 | 奥沙奈坦 Osanetant | 160492-56-8 | 5mg | 5800元 |
| 2024/01/25 | HY-14551 | 奥沙奈坦 Osanetant | 160492-56-8 | 10 mM * 1 mLin DMSO | 7740元 |
常见问题列表
生物活性
Osanetant (SR142801) 是一种选择性的 NK3 受体拮抗剂。Osanetant 有抗焦虑和抗抑郁的作用，并被研究用于精神分裂症。靶点
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NK3
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体内研究
Osanetant (SR142801; po; 1-10 mg/kg; 60 min before testing) significantly increases social interaction time.
Osanetant (ip; 5 and 10 mg/kg; 30 min before testing) decreases immobility time.
| Animal Model: | Male Mongolian gerbils of 7 weeks old (50-60 g) |
| Dosage: | 1, 3 and 10 mg/kg |
| Administration: | Po; 60 min before testing |
| Result: | Significantly increased social interaction time. |