1621585-17-8

中文名称 Pyrano[3,4-d][1,3]thiazin-2-amine, 8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydro-4-methyl-6-(3-methyl-5-isoxazolyl)-, (4R,4aR,6R,8aS)-

英文名称 Pyrano[3,4-d][1,3]thiazin-2-amine, 8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydro-4-methyl-6-(3-methyl-5-isoxazolyl)-, (4R,4aR,6R,8aS)-

CAS 1621585-17-8

分子式 C18H19F2N3O2S

分子量 379.42

MOL 文件 1621585-17-8.mol

1621585-17-8 结构式

基本信息应用领域

基本信息

中文别名

化合物 T28390

英文别名

PF9238
PF-9238
PF 9238
PF-06649283 >=98% (HPLC)
Pyrano[3,4-d][1,3]thiazin-2-amine, 8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydro-4-methyl-6-(3-methyl-5-isoxazolyl)-, (4R,4aR,6R,8aS)-

应用领域

用途一

PF9238 is a beta-secretase I inhibitor. Treatment with PF9238 results in the accumulation of autofluorescent granules in the retinas. PF9238 has a CatD potency of 12 uM in vivo.