168158-16-5
英文名称
Butanediamide,N1-hydroxy-2-methyl-N4-[(1S)-2-(methylamino)-2-oxo-1-phenylethyl]-3-(2-methylpropyl)-,(2S,3R)-
CAS
168158-16-5
分子式
C18H27N3O4
分子量
349.42
MOL 文件
168158-16-5.mol
168158-16-5 结构式
基本信息
英文别名
Butanediamide,N1-hydroxy-2-methyl-N4-[(1S)-2-(methylamino)-2-oxo-1-phenylethyl]-3-(2-methylpropyl)-,(2S,3R)-应用领域
用途一
KB-R7785 is a novel ADAM12 and MMP inhibitor, ameliorating cardiac function in a transverse aortic constriction (TAC) model by inhibiting the proteolytic activation of HB-EGF signaling, exerting its antidiabetic effect by ameliorating insulin sensitivity through the inhibition of TNF-alpha production.