172670-99-4
中文名称
3-羟基-N-(四氢-2-氧代-3-呋喃基)十四烷酰胺
英文名称
N-(3-Hydroxytetradecanoyl)-DL-hoMoserine lactone
CAS
172670-99-4
分子式
C18H33NO4
分子量
327.46
MOL 文件
172670-99-4.mol
172670-99-4 结构式
基本信息
中文别名
3-羟基-N-(四氢-2-氧代-3-呋喃基)十四烷酰胺 英文别名
N-(3-oxodecanoyl)-homoserine lactone3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide
N-(3-Hydroxytetradecanoyl)-DL-hoMoserine lactone
3-Hydroxy-N-(tetrahydro-2-oxo-3-furanyl)tetradecanamide
Tetradecanamide, 3-hydroxy-N-(tetrahydro-2-oxo-3-furanyl)-
N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone >=96% (HPLC), carbon 64.7-67.3 %
物理化学性质
沸点549.3±50.0 °C(Predicted)
密度1.04±0.1 g/cm3(Predicted)
储存条件-20°C
酸度系数(pKa)14.23±0.20(Predicted)
形态Solid
颜色White to off-white
常见问题列表
生物活性
N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone) 是来自溶藻弧菌菌株的 N-酰基高丝氨酸内酯 (AHL) 的成员。N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone 用于生物膜形成并具有抗菌活性。体外研究
Moderate levels of exogenous N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone; 10 and 20 μM) can induce or enhance biofilm formation and alter its structure, while high levels (40 and 100 μM) does not significantly improve and even inhibits biofilm formation in
V. alginolyticus
.
N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (2, 5, 10, 20 μM; 36 hours) increases the biofilms of strain N°24 significantly.
Moderate addition of N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (10 or 20 μM) also increases biofilm formation of non-AHL-producing peanut-nodulating bacteria.