175779-28-9

英文名称 (R)-TaClo

CAS 175779-28-9

分子式 C12H11Cl3N2

分子量 289.59

MOL 文件 175779-28-9.mol

175779-28-9 结构式

基本信息物理化学性质应用领域

基本信息

英文别名

(S)-1-TrichloroMethyl-1,2,3,4-Tetrahydro-β-carboline
(S)-2,3,4,9-Tetrahydro-1-(trichloroMethyl)-1H-pyrido[3,4-b]indole
1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1-(trichloromethyl)-, (1S)-

物理化学性质

沸点447.4±40.0 °C(Predicted)

密度1.480±0.06 g/cm3(Predicted)

酸度系数(pKa)16.74±0.40(Predicted)

应用领域

用途1

THe S-enatiomer of the dopaminergic and serotonergic neurotoxin 1-Trichloromethyl-1,2,3,4-Tetrahydro-β-carboline (TaClo). Liver enzymes produces TaClo via catalysis reaction of Tricloroethane with Try ptamine (T894600). TaClo destroys dopamine-producing cells and is a molecule of importance in the study of Parkinson鈥檚 disease.