1783-84-2
![1783-84-2 结构式](/CAS/GIF/1783-84-2.gif)
基本信息
顺式-8,11,14-二十烷三烯酸
HOMO-Γ-亚麻酸(C20:3)
全顺-8,11,14-二十碳三烯酸
二十碳三烯酸(顺-8,11,14)
顺式-8,11,14-二十碳三烯酸
顺 -8,11,14-二十碳三烯酸
顺式-8,11,14-二十烷三烯酸甲酯
顺式 - 8,11,14-二十碳三烯的酸
顺-8,11,14-二十碳三烯酸甲酯 (C20:3N6)
20:3(n-6)
Ro 12-1989
Diroleuton
Murepavadin
(8Z,11Z,14Z)
homo-γ-linolenic acid
w6-Eicosatrienoic acid
BishoMo-γ-linolenic Acid
HOMO-GAMMA-LINOLENIC ACID
物理化学性质
报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
2024/04/30 | E0640 | 全顺-8,11,14-二十碳三烯酸 all cis-8,11,14-Eicosatrienoic Acid | 1783-84-2 | 50mg | 985元 |
2024/01/16 | XW17838421 | 顺式-8,11,14-二十碳三烯酸 | 1783-84-2 | 5MG | 219元 |
2023/10/26 | E0640 | 全顺-8,11,14-二十碳三烯酸 all cis-8,11,14-Eicosatrienoic Acid | 1783-84-2 | 10mg | 420元 |
常见问题列表
Human Endogenous Metabolite
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Dihomo-γ-linolenic acid attenuates pro-inflammatory gene expression in human and mouse macrophages.
Dihomo-γ-linolenic acid (50 μM; 24 hours) attenuates IFN-γ induced phosphorylation of STAT1 on serine 727.
Dihomo-γ-linolenic acid attenuates IL-1β and TNF-α induced MCP-1 and ICAM-1 expression in human macrophages.
Dihomo-γ-linolenic acid attenuates chemokine-driven monocytic migration and macrophage foam cell formation.
Dihomo-γ-linolenic acid attenuates the expression of SR-A and CD36 in human macrophages.
Dihomo-γ-linolenic acid modulates mitochondrial respiration.
Dihomo-γ-linolenic acid modulates the properties of endothelial cells and VSMC.
Western Blot Analysis
Cell Line: | THP-1 macrophages |
Concentration: | 50 μM (pre-treated) |
Incubation Time: | 24 hours |
Result: | Attenuated IFN-γ induced phosphorylation of STAT1 on serine 727. |
Dihomo-γ-linolenic acid (8 mg/mouse; i.g; twice a week; for 35 days) inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA.
Animal Model: | Female nude mice (48 four-week old) |
Dosage: | 8 mg/mouse |
Administration: | Oral gavage, twice a week, for 35 days |
Result: | Suppressed metastasis potential in D5D-KD tumors. |