1800487-55-1
![1800487-55-1 结构式](/CAS/20210111/GIF/1800487-55-1.gif)
物理化学性质
沸点670.3±55.0 °C(Predicted)
密度1.31±0.1 g/cm3(Predicted)
酸度系数(pKa)14.46±0.46(Predicted)
形态Solid
颜色White to light yellow
应用领域
用途一
OT-82 is a potent NAMPT Inhibitor that targets the strong dependence of hematological malignancies on NAD biosynthesis. OT-82 showed strong efficacy against hematopoietic malignancies including acute myeloblastic and lymphoblastic adult and pediatric leukemias, erythroleukemia, multiple myeloma, and Burkitt's lymphoma in vitro and in mouse xenograft models.