188842-14-0
中文名称
188842-14-0
CAS
188842-14-0
分子式
C104H168N34O20S
分子量
2246.73
MOL 文件
188842-14-0.mol
更新日期
2024/07/07 16:58:00
![188842-14-0 结构式](/CAS/20210111/GIF/188842-14-0.gif)
常见问题列表
生物活性
Antennapedia Peptide 是由 16 个氨基酸残基组成的多肽,来源于果蝇转录因子 Antennapedia 的 60 个氨基酸序列的同源域,它同时是一种穿膜肽。体外研究
Antennapedia (Antp)-SMCC-cytochrome c conjugate (5 μg/mL) activates caspase-dependent apoptosis of HeLa cells. The Antp-SMCC-cytochrome c conjugate reduces the clonogenic survival of Hela cells, and inhibits clonogenic survival. ANTP-SmacN7 fusion protein can transduce and accumulate in cells, while SmacN7 alone cannot. ANTP-SmacN7 fusion proteins have a radiation-sensitising effect on EC109 cells. ANTP-SmacN7 combined with radiation does not promote further increases in caspase-3 protein expression, it increases the levels of cleaved caspase-3.