1924596-31-5
中文名称
MAL-AMIDO-PEG8-TFP ESTER
英文名称
Mal-amido-PEG8-TFP ester
CAS
1924596-31-5
分子式
C32H44F4N2O13
分子量
740.69
MOL 文件
1924596-31-5.mol
更新日期
2024/07/23 22:48:56
1924596-31-5 结构式
基本信息
中文别名
马来酰亚胺-八聚乙二醇-四氟苯酯马来酰亚胺-酰胺-八聚乙二醇-四氟苯酚酯
马来酰亚胺-酰胺-八聚乙二醇-四氟苯基酯
英文别名
Mal-NH-PEG8-TFPMal-amido-PEG8-TFP ester
4,7,10,13,16,19,22,25-Octaoxa-28-azahentriacontanoic acid, 31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-, 2,3,5,6-tetrafluorophenyl ester
应用领域
用途一
Mal-amido-PEG8-TFP ester is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains.