192939-46-1
中文名称
希美加群
英文名称
EXANTA
CAS
192939-46-1
分子式
C24H35N5O5
分子量
473.57
MOL 文件
192939-46-1.mol
更新日期
2024/07/06 13:39:35
![192939-46-1 结构式](/CAS/GIF/192939-46-1.gif)
基本信息
英文别名
EXANTAExarta
CS-1834
H 376/95
Exanta (TN)
XIMELEGATRAN
EXANTA/XIMELEGATRAN
Exanta (XiMelagatran)
Ximelagatran [USAN:INN]
Ximelagatran (JAN/USAN/INN)
常见问题列表
生物活性
Ximelagatran (H 376/95) 是一种口服活性凝血酶抑制剂,可选择性和竞争性地抑制游离和凝块结合的凝血酶。Ximelagatran 还是一种抗凝药物,具有快速起效的抗凝作用,可预测的,剂量依赖性的药代动力学和药效学。体外研究
Ximelagatran is an orally administered direct thrombin inhibitor under development as an anticoagulant agent for prophylaxis against and treatment of thromboembolism. Ximelagatran is rapidly absorbed and quickly converted into its active form Melagatran, a reversible, active-site inhibitor of both free and clot-bound thrombin that has stable and reproducible pharmacokinetic properties. Initial studies have shown Ximelagatran to have good efficacy and safety in the prevention of venous thromboembolism after total knee or total hip replacement.