2031170-96-2
英文名称
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-dichloro-3'-hydroxy-6'-(4-hydroxy-3,5-diiodophenoxy)-
CAS
2031170-96-2
分子式
C26H12Cl2I2O6
分子量
745.08
MOL 文件
2031170-96-2.mol
更新日期
2023/03/20 15:41:21
2031170-96-2 结构式
基本信息
英文别名
HKOH-1Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-dichloro-3'-hydroxy-6'-(4-hydroxy-3,5-diiodophenoxy)-
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-dichloro-3'-hydroxy-6'-(4-hydroxy-3,5-diiodophenoxy)-
物理化学性质
沸点698.9±55.0 °C(Predicted)
密度2.24±0.1 g/cm3(Predicted)
酸度系数(pKa)6.83±0.25(Predicted)
形态Solid
颜色White to off-white
常见问题列表
生物活性
HKOH-1 是高灵敏度和选择性的荧光探针，可用于检测内源性羟基自由基。体外研究
HKOH-1 shows absorption peaks at 500 nm. In absence of
•
OH, HKOH-1 is non-fluorescent.
HKOH-1r (0.1-50 μM; 24 h) shows negligible or no cytotoxicity in both RAW264.7 cells and Hela cells.
HKOH-1r (5 μM; 30 min) detects endogenous
•
OH in the flow cytometry platform in RAW264.7 cells.