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2049025-67-2

中文名称 AB005-11杂质
英文名称 (S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((S)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
CAS 2049025-67-2
分子式 C40H57N5O7
分子量 719.91
MOL 文件 2049025-67-2.mol
更新日期 2024/11/08 15:25:17
2049025-67-2 结构式 2049025-67-2 结构式

基本信息

中文别名
卡非佐米杂质13
卡非佐米杂质39
AB005-11杂质
英文别名
Kyprolis Impurity 39
(R,S)-Epoxy Leucine Carfilzomib
(S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((S)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide

应用领域

用途一
(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1R)-3-methyl-1-[[(2S)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide is an impurity of Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
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