2055024-37-6
中文名称
Acid-PEG4-Sulfone-PEG4-Acid
英文名称
Acid-PEG4-Sulfone-PEG4-Acid
CAS
2055024-37-6
分子式
C22H42O14S
分子量
562.63
MOL 文件
2055024-37-6.mol
2055024-37-6 结构式
基本信息
中文别名
羧酸-四聚乙二醇-砜-四聚乙二醇-羧酸羧酸-四聚乙二醇-SULFONE-四聚乙二醇-羧酸
英文别名
Sulfone-Bis-PEG4-acidAcid-PEG4-Sulfone-PEG4-Acid
4,7,10,13,19,22,25,28-Octaoxa-16-thiahentriacontanedioic acid, 16,16-dioxide
应用领域
用途一
Acid-PEG4-Sulfone-PEG4-acid contains two PEG-acid chains connected by a sulfone group. The sulfone group can be conjugated with thiol groups of proteins. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG spacer increases the water solubility of the compound in aqueous media.