20633-84-5
中文名称
忍冬苷
英文名称
LONICERIN
CAS
20633-84-5
分子式
C27H30O15
分子量
594.52
MOL 文件
20633-84-5.mol
更新日期
2024/03/04 17:20:50
![20633-84-5 结构式](/CAS/20211123/GIF/20633-84-5.gif)
基本信息
中文别名
忍冬苷 英文别名
Luteolin-7-O-rhamnosideLuteoline-7-rhamnoglucoside
Luteolin 7-O-Rutinoside (Scolymoside)
Luteolin 7-rutinoside >=95% (LC/MS-ELSD)
所属类别
天然产物:生物碱物理化学性质
熔点192-196 °C
沸点954.0±65.0 °C(Predicted)
密度1.76±0.1 g/cm3(Predicted)
储存条件-20°C
溶解度DMSO: soluble
酸度系数(pKa)6.10±0.40(Predicted)
形态A solid
颜色Light yellow to yellow
常见问题列表
生物活性
Luteolin-7-rutinoside 具有抗关节炎和抗真菌的双重作用,可用于研究白色念珠菌感染引起的真菌关节炎。体外研究
At a dose of 10 μg Luteolin-7-rutinoside (lonicerin)/mL, there is an approximately 47% decrease of the proliferation as compared to proliferation of Luteolin-7-rutinoside treated (control) T cells (p<0.05). Luteolin-7-rutinoside at 40 μg/mL dose give almost the same rate of T cell proliferation as does 20 μg/mL dose of Luteolin-7-rutinoside. The suppressive activity is dose dependent. Luteolin-7-rutinoside treatment swifts Th1-Th2 balance away from Th1-toward Th2-type responses. Luteolin-7-rutinoside inhibits nitric oxide (NO) production from macrophages.