206658-92-6
基本信息
盐酸他克林水合物
他克林盐酸盐水合物
THA 盐酸盐 水合物
单满吖啶氨 盐酸盐 水合物
9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%
报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
2024/08/19 | S3639 | 9-氨基-1,2,3,4-四氢吖啶 盐酸盐 水合物 Tacrine hydrochloride hydrate | 206658-92-6 | 25mg | 1040.61元 |
2024/08/19 | S3639 | Tacrine hydrochloride hydrate | 206658-92-6 | 1g | 7944.3元 |
常见问题列表
Target | Value |
HNMT
() | |
cholinesterase
() |
Tacrine hydrochloride hydrate (12.5 to 37.5 nM) inhibits venom acetylcholinesterase as well as human serum butyrylcholinesterase in a concentration-dependent manner. The IC 50 is 31 nM for snake venom AChE and 25.6 nM for human BChE.
Pretreatment with Tacrine hydrochloride hydrate also modifies absolute levels of cocaine self-administration during reacquisition. Body weight declines approximately one-half percent over four days of treatment with intravenous Tacrine hydrochloride hydrate. Delivery of Tacrine hydrochloride hydrate by osmotic pump does not alter either linear- or repeated- cocaine-induced locomotor activity. There is no significant main effect or interaction with Tacrine hydrochloride hydrate treatment on active lever responding during reinstatement. Post hoc comparisons indicate that rats self-administering cocaine has significantly lower alkaline phosphatase levels, relative to Tacrine hydrochloride hydrate- but not saline- treated rats evaluated by conditioned-place preference.