2089-82-9
2089-82-9 结构式
物理化学性质
储存条件-20°C储存
溶解度DMSO: 5 mg/mL (20.30 mM)
沸点522.2±15.0 °C(Predicted)
密度1.393±0.06 g/cm3(Predicted)
酸度系数(pKa)7.15±0.30(Predicted)
形态Solid
颜色Yellow to orange
常见问题列表
生物活性
sAJM589 是一种 Myc 抑制剂，能干扰 Myc- max 异二聚体的形成，其 IC50 值为 1.8 μM。靶点
IC50: 1.8 μM (Myc)
体外研究
sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose dependent manner, with an IC
50
of 1.8 μM.
sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells.