211735-76-1
![211735-76-1 结构式](/CAS/GIF/211735-76-1.gif)
基本信息
Org2444
Org 24448
FARAMPATOR
CX-691
ORG2444
Org24448, CX-691
Farampator (CX691)
CX 691
ORG 24448
CX-691
CX691
Methanone, 2,1,3-benzoxadiazol-5-yl-1-piperidinyl-
物理化学性质
常见问题列表
Farampator has potential in treating disorders characterised by cognitive deficits such as Alzheimer's disease and schizophrenia. CX691 attenuates a scopolamine-induced impairment of cued fear conditioning following acute administration (0.1 mg/kg p.o.) and a temporally induced deficit in novel object recognition following both acute (0.1 and 1.0 mg/kg p.o.) and sub-chronic (bi-daily for 7 days) administration (0.01, 0.03, 0.1 mg/kg p.o.). It also improves attentional set-shifting following sub-chronic administration (0.3 mg/kg p.o.). Farampator (500 mg) unequivocally improves short-term memory but appeares to impair episodic memory. Furthermore, it tends to decrease the number of switching errors in the CTMT. Drug-induced side effects (SEs) included headache, somnolence and nausea. Subjects with SEs has significantly higher plasma levels of farampator than subjects without SEs.