2170240-99-8
中文名称
(2-PYRIDYLDITHIO)-PEG4-PROPARGYL
英文名称
(2-pyridyldithio)-PEG4-propargyl
CAS
2170240-99-8
分子式
C16H23NO4S2
分子量
357.49
MOL 文件
2170240-99-8.mol
更新日期
2023/06/09 11:23:36
2170240-99-8 结构式
物理化学性质
沸点465.6±45.0 °C(Predicted)
密度1.18±0.1 g/cm3(Predicted)
酸度系数(pKa)1.81±0.12(Predicted)
形态Liquid
颜色Colorless to light yellow
应用领域
用途一
(2-pyridyldithio)-PEG4-propargyl is a PEG linker which contains a pyridyl disulfide moiety and a propargyl group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH levels. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.