2183440-70-0
中文名称
N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid
英文名称
N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid
CAS
2183440-70-0
分子式
C24H47N5O11
分子量
581.66
MOL 文件
2183440-70-0.mol
2183440-70-0 结构式
应用领域
用途一
N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a heterotrifunctional PEG linker containing azide (N3), amine(NH2), and carboxylic acid(CO2H) moieties. The azide can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. An amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.