218791-21-0
218791-21-0 结构式
基本信息
CG 4419
M-40403
SC72325
CG-4419
SC-72325
SC 72325
IMISOPASEM MANGANESE
Imisopasem manganese(m40403)
M40403
M 40403
M-40403
CG4419
CG 4419
CG-4419
SC72325
SC-72325
SC 72325
IMISOPASEM MANGANESE
物理化学性质
DMF:3.0(Max Conc. mg/mL);6.21(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);41.38(Max Conc. mM)
PBS (pH 7.2):3.0(Max Conc. mg/mL);6.21(Max Conc. mM)
Water:16.0(Max Conc. mg/mL);33.1(Max Conc. mM)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-13336 | 218791-21-0 Imisopasem manganese | 218791-21-0 | 2mg | 990元 |
| 2024/04/30 | HY-13336 | 218791-21-0 Imisopasem manganese | 218791-21-0 | 5mg | 1700元 |
| 2024/04/30 | HY-13336 | 218791-21-0 Imisopasem manganese | 218791-21-0 | 10mM * 1mLin Water | 1793元 |
常见问题列表
M40403 is a small molecule, synthetic manganese containing superoxide dismutase mimetic (SODm) that removes superoxide anions without interfering with other reactive species known to be involved in inflammatory responses (e.g. nitric oxide, NO and peroxynitrite, ONOO-).
M40403 is a small-molecule superoxide dismutase mimetic that has shown efficacy in animal model disease states in which superoxide anions are thought to play a key role. M40403 inhibits the inflammatory response following the intrapleural injection of carrageenan in rats. All parameters of inflammation are attenuated by M40403 except for NOx, PGE2 and IL-10 which remains unaltered. Decreased apoptosis of the large and particularly the small bowel and marked recovery of both lymphoid and hematopoietic tissues occurs in the M40403 pre-treated mice. M40403 is effective in reducing TBI-induced tissue destruction and has potential as a new radioprotective agent.