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2219331-30-1

中文名称 BB-F-YNE
英文名称 BB-F-Yne
CAS 2219331-30-1
分子式 C28H26FN5O
分子量 467.54
MOL 文件 2219331-30-1.mol
2219331-30-1 结构式 2219331-30-1 结构式

基本信息

英文别名
BB-F-Yne
所属类别
生物化工:抑制剂

物理化学性质

储存条件-20°C储存
溶解度DMF: 5 mg/mL; DMF:PBS (pH 7.2) (1:5): 0.16 mg/mL; DMSO: 20 mg/mL
形态结晶固体

应用领域

用途一
BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-F-Yne inhibits PAD1-4 and has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.
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