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2227199-31-5

中文名称 托法替尼杂质
英文名称 butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate
CAS 2227199-31-5
分子式 C20H29N5O3
分子量 387.476
MOL 文件 2227199-31-5.mol
更新日期 2024/11/13 09:24:53
2227199-31-5 结构式 2227199-31-5 结构式

基本信息

中文别名
托伐替布杂质26
托法替尼杂质135
托法替布相关杂质40
托法替布相关化合物40
枸橼酸托法替布杂质 PF-05211077
3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯并[2,3-D] 嘧啶-4-基)氨基)哌啶-1-基)-3-氧代丙酸丁酯 (托法替布杂质26)
英文别名
Tofacitib related impurities 40
N-Butyl 3-Oxopropanoate Tofacitinib
Butyl 3-[4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanoate
butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate
所属类别
分析化学:药典标准品和杂质标准品

应用领域

用途一
N-Butyl 3-oxopropanoate Tofacitinib is an impurity of Tofacitinib(T528000) which is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
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