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2280796-94-1

中文名称 RT-AM
英文名称 RT-AM
CAS 2280796-94-1
分子式 C??H??N?O??
分子量 555.5
MOL 文件 2280796-94-1.mol
2280796-94-1 结构式 2280796-94-1 结构式

基本信息

英文别名
RT-AM

物理化学性质

沸点790.8±60.0 °C(Predicted)
密度1.458±0.06 g/cm3(Predicted)
酸度系数(pKa)3.62±0.20(Predicted)
形态Solid
颜色Pink to red
RT-AM价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2024/04/30HY-108715ART-AM
RT-AM
2280796-94-11mg3500元
2023/03/20HY-108715ART-AM
RT-AM
2280796-94-110 mM * 1 mLin DMSO21386元

常见问题列表

生物活性
RT-AM是real thiol前体药物。Real Thiol 是一种基于可逆反应的荧光探针,可以定量监测活细胞中谷胱甘肽的实时动态变化。
体外研究

To enhance the cell permeability of Real Thiol, the carboxylic acid groups is converted to acetoxymethyl (AM) esters, which are readily hydrolysed by esterases to regenerate Real Thiol inside cells. For cells treated with the RT-AM, real-time ratiometric images of the rapid changes of intracellular GSH concentrations in single cells can be generated by dividing the fluorescence intensity values for the 405 nm channel by the 488 nm channel at each corresponding pixel.

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