2375554-02-0
中文名称
化合物 SENEXIN C
英文名称
Senexin C
CAS
2375554-02-0
分子式
C28H27N5O
分子量
449.56
MOL 文件
2375554-02-0.mol
更新日期
2024/12/03 21:42:32
2375554-02-0 结构式
应用领域
用途一
Senexin C exhibits potent CDK8/19 inhibitory activity with high selectivity. Senexin C is more metabolically stable and provides a more sustained inhibition of CDK8/19-dependent cellular gene expression when compared with the prototype inhibitor Senexin B. Senexin C inhibits MV4-11 leukemia growth in a systemic in vivo model with good tolerability.