2409969-94-2
![2409969-94-2 结构式](/CAS/20210305/GIF/2409969-94-2.gif)
常见问题列表
生物活性
m-PEG10-acid 是一种不可降解 (non-cleavable) 的含 10 个单元 PEG 的 ADC linker,可用于合成抗体偶联药物 (ADC)。m-PEG10-acid 还是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。靶点
PEGs
|
Non-cleavable
|
体外研究
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.