2507-24-6
2507-24-6 结构式
基本信息
中文别名
泡蛙肽PHYSALAEMIN肽
英文别名
FI 6422Physalemin
PHYSALAEMIN
Physalaemine
PHYSALAEMIN ACOH 3H2O
Physalemin(7CI,8CI,9CI)
Physalaemin, ≥97% (HPLC)
GLP-ALA-ASP-PRO-ASN-LYS-PHE-TYR-GLY-LEU-MET-NH2
PYR-ALA-ASP-PRO-ASN-LYS-PHE-TYR-GLY-LEU-MET-NH2
PGLU-ALA-ASP-PRO-ASN-LYS-PHE-TYR-GLY-LEU-MET-NH2
所属类别
生物化工：多肽常见问题列表
用途
Physalaemin最初是从Physalaemus frog中分离出来的，是一种与P物质密切相关的速激肽。它是一种有效的血管扩张剂，具有降压作用。
生物活性
Physalaemin是一种非哺乳动物类的速激肽，选择性地高亲和力结合到神经激肽-1 (NK1) 受体。靶点
Neurokinin-1 (NK1) receptor
体外研究
Physalaemin (PHY), an undecapeptide with the sequence pGlu-Ala-Asp-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2, is a member of the tachykinin family of neuropeptides. PHY is very close to the mammalian tachykinin substance P (SP) in its function and chemical composition, and SP is well studied and characterized. Physalaemin is a bradykinin potentiating peptide (BPP-5a).