263251-78-1
263251-78-1 结构式
基本信息
中文别名
化合物 T17000 英文别名
TavilermideGlycine, N-(2-hydroxy-5-nitrobenzoyl)-L-α-glutamyl-L-lysyl-L-homoseryl-, cyclic (1→3)-ether
3-((4S,7S,10S)-7-(4-aminobutyl)-4-((carboxymethyl)carbamoyl)-14-nitro-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12-decahydro-2H-benzo[b][1,5,8,11]oxatriazacyclotetradecin-10-yl)propanoic acid(WXG02263)
物理化学性质
沸点1122.4±65.0 °C(Predicted)
密度1.341±0.06 g/cm3(Predicted)
储存条件-20°C储存
酸度系数(pKa)3.59±0.10(Predicted)
形态Solid
颜色White to off-white
水溶解性Water : 5 mg/mL (8.61 mM; adjust pH to 3-4 with HCl)
263251-78-1价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-17622 | 263251-78-1 Tavilermide | 263251-78-1 | 1mg | 1500元 |
| 2025/02/08 | HY-17622 | 263251-78-1 Tavilermide | 263251-78-1 | 5mg | 4000元 |
| 2024/08/19 | HY-17622 | 263251-78-1 Tavilermide | 263251-78-1 | 10mg | 6400元 |
常见问题列表
生物活性
Tavilermide 是一种选择性的 TrkA 部分激动剂。靶点
TrkA
体外研究
Tavilermide (MIM-D3) is a tyrosine kinase TrkA receptor agonist, which can be used to treat dry eye.Tavilermide is a proteolytically stable, cyclic peptidomimetic that has been shown to be a partial TrkA receptor agonist. Tavilermide demonstrates activities similar to NGF (but does not bind to the p75NTR receptor) and can potentiate the effects of suboptimal concentrations of NGF.