2918768-28-0
中文名称
[Met5]-Enkephalin, amide TFA
英文名称
[Met5]-Enkephalin, amide TFA
CAS
2918768-28-0
分子式
C??H??F?N?O?S
基本信息
英文别名
[Met5]-Enkephalin, amide TFA[Met5] Enkephalin, amide TFA,[Met-5]-Enkephalin, amide TFA,[Met5]Enkephalin, amide TFA
常见问题列表
生物活性
[Met5]-Enkephalin, amide TFA 是一种 δ 和 ζ 阿片受体 (opioid receptor) 激动剂。靶点
δ and ζ opioid receptor
体外研究
[Met5]-Enkephalin at 0.1 nM, 10 nM, and 1 μM significantly reduces the total number of glial cells in culture. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC 50 value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine.