32542-16-8
中文名称
4-(4-Ethoxy-benzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester
英文名称
4-(4-Ethoxy-benzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester
CAS
32542-16-8
分子式
C18H23NO3
分子量
301.38
MOL 文件
32542-16-8.mol
32542-16-8 结构式
基本信息
中文别名
4-(4-乙氧基苄基)-3,5-二甲基-1H-吡咯-2-羧酸乙酯 英文别名
ethyl 4-(4-ethoxybenzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylateethyl 4-[(4-ethoxyphenyl)methyl]-3,5-dimethyl-1H-pyrrole-2-carboxylate
4-(4-Ethoxy-benzyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester
1H-Pyrrole-2-carboxylic acid, 4-[(4-ethoxyphenyl)methyl]-3,5-dimethyl-, ethyl ester
应用领域
用途一
DSM43 is a dihydroorotate dehydrogenase (DHODH) inhibitor. Malaria puts at risk nearly half the world's population and causes high mortality in sub-Saharan Africa, while drug resistance threatens current therapies. The pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase (DHODH) is a validated target for malaria treatmen