371135-20-5
中文名称
化合物 T28868
英文名称
ethyl {2-methyl-3-[2-(naphtho[2,1-b]furan-2-ylcarbonyl)carbohydrazonoyl]-1H-indol-1-yl}acetate
CAS
371135-20-5
分子式
C27H23N3O4
分子量
453.489
MOL 文件
371135-20-5.mol
371135-20-5 结构式
基本信息
中文别名
化合物 T28868 英文别名
ethyl {2-methyl-3-[2-(naphtho[2,1-b]furan-2-ylcarbonyl)carbohydrazonoyl]-1H-indol-1-yl}acetate应用领域
用途一
STK899704 is a novel tubulin inhibitor, preventing the polymerization of purified tubulin in vitro and depolymerizing microtubule in cultured cells leading to mitotic arrest, associated with increased Cdc25C phosphorylation and the accumulation of both cyclin B1 and polo-like kinase 1 (Plk1), and apoptosis.