3796-63-2
中文名称
(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
英文名称
(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
CAS
3796-63-2
分子式
C23H38O
分子量
330.55
MOL 文件
3796-63-2.mol
3796-63-2 结构式
基本信息
中文别名
(5E,9E,13E)-6,10,14,18-四甲基十九碳-5,9,13,17-四烯-2-酮 英文别名
E-0671(5E,9E,13E)-Geranylgeranylacetone
(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
(5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-, (E,E,E)-
5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-, (5E,9E,13E)-
所属类别
有机原料:酮类化合物物理化学性质
沸点442.2±24.0 °C(Predicted)
密度0.872±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度DMSO: 5 mg/mL (15.13 mM)
形态Liquid
颜色Colorless to light yellow
常见问题列表
生物活性
(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) 是 Teprenone 的同分异构体,具有抗溃疡活性。(5E,9E,13E)-Teprenone 能诱导 HSP 基因的转录激活,可能导致应激条件下的胃粘膜防御提升。体外研究
(5E,9E,13E)-Teprenone might transiently activate the transcription of HSP70 gene.
The heat shock element–binding activity reflects the activation of heat shock factor 1 in response to (5E,9E,13E)-Teprenone.
体内研究
(5E,9E,13E)-Teprenone induces hat sock proteins accumulations in rat gastric mucosa.
Animal Model: | Male Wister strain rats (≈250 g) |
Dosage: | 200 mg/kg |
Administration: | Oral administration |
Result: | Caused accumulations of all of HSP90, HSP70, HSC70 and HSP60 within 60 minutes. |