473930-22-2
473930-22-2 结构式
物理化学性质
熔点248.5-252 °C(Solv: methanol (67-56-1))
密度1.322±0.06 g/cm3(Predicted)
酸度系数(pKa)10.30±0.20(Predicted)
形态Solid
颜色Off-white to light yellow
应用领域
用途一
SM-276001 is a selective and potent TLR7 agonist. SM-276001 is can induce antitumor immune responses when dosed either intratracheally or orally. Oral administration of SM-276001 leads to the induction of IFNα, TNFα and IL-12p40 and a reduction in tumor burden in the Balb/c syngeneic Renca and CT26 models.