475193-31-8
中文名称
2-甲基硫代二磷酸腺苷
英文名称
2-(METHYLTHIO)ADENOSINE 5'-DIPHOSPHATE TRISODIUM SALT 2-(METHYLTHIO)ADENOSINE 5'-DIPHOSPHATE TRISODIUM SALT 2-(METHYLTH
CAS
475193-31-8
分子式
NULL
MOL 文件
475193-31-8.mol
475193-31-8 结构式
基本信息
中文别名
化合物 T23581 英文别名
2-Methylthio-ADP trisodium salt hydrate2-Methylthioadenosine diphosphate (sodium salt)
2-(methylthio)adenosine 5'-diphosphate trisodium salt
2-(Methylthio)adenosine 5′-diphosphate trisodium salt hydrate
2-(Methylthio)adenosine 5′-trihydrogen diphosphate trisodium salt hydrate
2-(METHYLTHIO)ADENOSINE 5'-DIPHOSPHATE TRISODIUM SALT 2-(METHYLTHIO)ADENOSINE 5'-DIPHOSPHATE TRISODIUM SALT 2-(METHYLTH
2-(Methylthio)adenosine 5′-diphosphate trisodium salt hydrate,2-(Methylthio)adenosine 5′-trihydrogen diphosphate trisodium salt hydrate, 2-Methylthio-ADP trisodium salt hydrate
常见问题列表
生物活性
2-Methylthioadenosine diphosphate trisodium (2-Methylthio-ADP trisodium) 是一种有效的嘌呤能 P2Y 受体激动剂,对人 P2Y13、小鼠 P2Y13 和人 P2Y12 的 EC50 分别为 19、6.2 和 5 nM。2-Methylthioadenosine diphosphate trisodium 对人 P2Y1 和大鼠 P2Y6 的 pEC50 分别为 8.29 和 5.75。2-Methylthioadenosine diphosphate trisodium 诱导血小板聚集和形态改变,并抑制前列腺素E1作用下血小板内环腺苷酸的积累。体外研究
2-Methylthioadenosine diphosphate trisodium (2-Methylthio-ADP trisodium) is a powerful aggregating agent for human platelets. 2-Methylthioadenosine diphosphate trisodium is also a powerful inhibitor of the accumulation of cyclic AMP in intact platelets exposed to PGE1 and a phosphodiesterase inhibitor.