49642-07-1
49642-07-1 结构式
基本信息
中文别名
化合物 T13011抑胃酶氨酸STATINE
STATINE抑胃酶氨酸
(3S,4S)-(-)-他汀
英文别名
STATINSTATINE
H-STA-OH
S)-Statine
LEU-STATINE
4S)-Statine
(S,S)-Statine
H-STA(3S,4S)-OH
(3S,4S)-STATINE
H-(3S,4S)-STA-OH
物理化学性质
熔点209 °C
比旋光度D15 -20° (c = 0.64 in water)
沸点306.53°C (rough estimate)
密度1.1233 (rough estimate)
折射率1.4476 (estimate)
储存条件2-8°C
溶解度0.5 M HCl: 50 mg/mL, clear, very faintly yellow
酸度系数(pKa)3.97±0.10(Predicted)
形态Solid
颜色White to off-white
Merck13,8879
常见问题列表
生物活性
Statine 是一种罕见的氨基酸，在胃蛋白酶抑制剂的序列中出现两次, 胃蛋白酶抑制剂是一种对胃蛋白酶和其他酸性蛋白酶有抑制作用的蛋白酶抑制剂。体外研究
Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases. Statine is also an analog of the previously proposed transition state for catalysis by pepsin and other acid proteases.