50602-77-2

英文名称 methotrexate di-n-butyl ester

CAS 50602-77-2

分子式 C28H38N8O5

分子量 566.65

MOL 文件 50602-77-2.mol

50602-77-2 结构式

基本信息应用领域

基本信息

英文别名

DBMTX
Dibutyl methotrexate
methotrexate di-n-butyl ester
(+)-N-[p-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]-L-glutamic acid dibutyl ester
(+)-N-[p-[[(2,4-Diaminopteridine-6-yl)methyl]methylamino]benzoyl]-L-glutamic acid dibutyl ester
L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, dibutyl ester (9CI)

应用领域

用途一

Methotrexate di-n-butyl ester is an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofoltae dehydrogenase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.