52906-92-0
52906-92-0 结构式
基本信息
胃动素,猪
胃动素 (人类,猪)
胃动素,猪, ≥97% (HPLC)
MOTILIN, PORCINE
MOTILIN PORCINE ≥97%
FVPIFTYGELQRMQEKERNKGQ
Motilin, porcine, ≥97% (HPLC)
Gastricmotorstimulatorypeptide
Motilin (26-47), human, porcine
GASTRIC MOTOR STIMULATORY PEPTIDE, PORCINE
PHE-VAL-PRO-ILE-PHE-THR-TYR-GLY-GLU-LEU-GLN-ARG-MET-GLN-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN
H-PHE-VAL-PRO-ILE-PHE-THR-TYR-GLY-GLU-LEU-GLN-ARG-MET-GLN-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN-OH
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-P1037 | 胃动素 Motilin (26-47), human, porcine | 52906-92-0 | 500μg | 900元 |
| 2024/04/30 | HY-P1037 | 胃动素 Motilin (26-47), human, porcine | 52906-92-0 | 1mg | 1500元 |
| 2024/04/30 | HY-P1037 | 胃动素 Motilin (26-47), human, porcine | 52906-92-0 | 5mg | 4500元 |
常见问题列表
EC50: 0.3 nM (motilin receptor, Chinese hamster ovary cell)
Ki: 2.3 nM (motilin receptor, Chinese hamster ovary cell)
[Bpa 1 ,Ile 13 ]motilin is a full agonist at the motilin receptor that increases intracellular calcium in a concentration-dependent manner (EC 50 = 1.5 ± 0.4 nM). Motilin binds with high affinity (IC 50 0.7± 0.2 nM) to receptors on smooth muscle cells. Motilin selectively activates G(q) and G(13), stimulates G alpha(q)-dependent phosphoinositide (PI) hydrolysis and 1,4,5-trisphosphate (IP(3))-dependent Ca 2+ release, and increases cytosolic free Ca 2+ . Motilin induces a biphasic, concentration-dependent contraction (EC 50 = 1.0 +/- 0.2 nM), consisting of an initial peak followed by a sustained contraction.