53609-64-6
53609-64-6 结构式
物理化学性质
沸点288.88°C (rough estimate)
密度1.2266 (rough estimate)
折射率1.4650 (estimate)
储存条件2-8°C
形态viscous liquid
颜色yellow
常见问题列表
生物活性
N-Bis(2-hydroxypropyl)nitrosamine 是一种具有致癌作用的试剂。体外研究
N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity.
体内研究
N-Bis(2-hydroxypropyl)nitrosamine causes the tumors to develop in the lung, liver, and thyroid of rats at a dose of 100 ppm, in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at a dose of 500 ppm, and in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at both doses. Bisphenol A (BPA) enhances the susceptibility to thyroid carcinoma stimulated by N-Bis(2-hydroxypropyl)nitrosamine (DHPN; 2800 mg/kg) in rats.