53696-59-6

中文名称 8-叠氮酰苷-5'-三磷酸钠

CAS 53696-59-6

分子式 C10H15N8O13P3

分子量 548.19

MOL 文件 53696-59-6.mol

53696-59-6 结构式

基本信息安全数据常见问题列表

基本信息

中文别名

8-叠氮酰苷-5'-三磷酸钠

英文别名

8-N3-ATP SODIUM SALT
8-azidoadenosine5’-triphosphate
8-azido-ATP - 10mM aqueous solution
8-azidoadenosine5’-triphosphatesodium
8-Azido-D-adenosine5'-triphosphatesodiumsalt
8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT
8-AZIDOADENOSINE-5'-O-TRIPHOSPHATE SODIUM SALT
Adenosine 5'-(tetrahydrogen triphosphate), 8-azido-
8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT USP/EP/BP
8-azidoadenosine-5’-o-triphosphate(8-n3-atp),sodiumsalt

安全数据

危险品标志Xi

常见问题列表

生物活性

8-Azido-ATP 是一个光解性的核苷酸类似物，用于鉴定蛋白，如依赖于 DNA 的 RNA 聚合酶。

体外研究

8-Azido-ATP can be used to identify the viral RNA polymerase on the basis of the ability of the analog to inhibit transcription activity associated with rotavirus particles on exposure to UV light.
8-Azido-ATP (azido-ATP) decreases viral transcription in a dose-dependent manner.
8-Azido-ATP blocks Kir6.2ΔC26 currents rather less potently than ATP, half-maximal inhibition (Ki) occurring at 2.8 ± 0.4 mM (n = 6) compared with 172 ± 7 mM for ATP (n = 6). The Hill coefficients were 0.9 ± 0.2 for 8-azido-ATP and 1.3 ± 0.1 for ATP.