579511-43-6
579511-43-6 结构式
应用领域
用途一
CRA-19156 is a potent HDAC8 inhibitor. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from lysines near the N termini of histones. This reaction promotes the condensation of chromatin, leading to repression of transcription. HDAC deregulation has been linked to several types of cancer, suggesting a potential use for HDAC inhibitors in oncology.