58020-43-2
中文名称
4-羟基妥洛特罗
英文名称
1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol
CAS
58020-43-2
分子式
C12H18ClNO2
分子量
243.73
MOL 文件
58020-43-2.mol
更新日期
2024/06/12 17:31:27
58020-43-2 结构式
基本信息
中文别名
4-羟基妥洛特罗 英文别名
HOKU 814-Hydroxytulobuterol
4-HYDROXYTULOBUTEROL
HOKU 81
HOKU81
1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol
2-Chloro-α-[(tert-butylamino)methyl]-4-hydroxybenzenemethanol
Benzenemethanol,2-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-
Benzenemethanol, 2-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-
2-Chloro-alpha-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxybenzenemethanol
常见问题列表
生物活性
HOKU-81 (4-Hydroxytulobuterol) 是 Tulobuterol (HY-B1810) 的代谢产物之一。HOKU-81 是一种有效的选择性 β2-肾上腺素受体刺激剂。HOKU-81 具有支气管扩张作用。靶点
|
Beta-2 adrenergic receptor
|
体外研究
HOKU-81 (4-Hydroxytulobuterol) is approximately 8 times more potent than tulobuterol, approximately twice as potent as salbutamol, and approximately as potent as isoprenaline in relaxing effect on the isolated tracheal smooth muscle preparation of guinea pigs.