59943-31-6

中文名称 DU 717

英文名称 DU 717

CAS 59943-31-6

分子式 C12H15ClN4O2S

分子量 314.79

MOL 文件 59943-31-6.mol

更新日期 2023/03/17 20:03:07

59943-31-6 结构式

基本信息物理化学性质常见问题列表

基本信息

中文别名

化合物DU717
化合物 T11109

英文别名

DU 717
7-chloro-3-(4-methyl-1-piperazinyl)-2H-1,2,4-benzothiadiazine 1,1-dioxide
2H-1,2,4-Benzothiadiazine, 7-chloro-3-(4-methyl-1-piperazinyl)-, 1,1-dioxide

物理化学性质

密度1.3907 (rough estimate)

折射率1.5630 (estimate)

储存条件-20°C储存

溶解度溶于二甲基亚砜

常见问题列表

生物活性

DU-717 是一种抗高血压剂。

体内研究

A gas chromatographic method has been developed which enables accurate determination of a new antihypertensive agent, DU-717, in plasma. Accurate determinations are possible over a concentration range from 10 to 150 ng/mL of DU-717 in plasma at a relative standard deviation of 6.2%. The minimum detectable concentration is 1 ng/mL. Plasma levels of DU-717 in spontaneously hypertensive and normotensive rats following single oral administrations (10 mg/kg) have also been determined.