61220-69-7
61220-69-7 结构式
物理化学性质
沸点541.3±50.0 °C(Predicted)
密度1.372±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)4.14±0.10(Predicted)
形态Solid
颜色White to off-white
常见问题列表
溶解度
体外：在DMSO中10mM 。
用途
硫平酸是一种二苯并噻吩，是具有口服活性且高度有效的抗炎，镇痛和解热剂。
体内研究
Tiopinac (0.03-110 mg/kg) has 40 times the antiphlogistic potency of phenylbutazone. The dose required to reduce paw swelling by 30% is approximately 0.5 mg/kg. Tiopinac does not elicit overt side effects at the 20 mg/kg/day dose. Tiopinac causes a dose-related reversal of the decreases body weight caused by the adjuvant disease, the weight of those rats receiving 0.135 and 0.4 mg/kg/day being significantly greater than that of the positive controls. Tiopinac (0.3-30 mg/kg) is highly potent in inhibiting the pain evoked in the yeastinflamed hind paw of the rat.